Best price vacation rentals in Seneca, SC, USA • 150 Listings
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Seneca, SC, USA Vacation Rentals | 

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5.0 (24)
Seneca Townhome on Lake Hartwell < 4 Mi to Clemson
Up to 6 guests
Vrbo$234
Airbnb$254
Average Nightly Rate
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5.0 (69)
Seneca Home w/Porch & Private Dock on Lake Keowee!
Up to 16 guests
Airbnb$499
Vrbo$604
Average Nightly Rate
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5.0 (57)
NEW Lake Keowee Home minutes from Clemson
Up to 17 guests
Vrbo$707
Airbnb$718
Average Nightly Rate
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5.0 (26)
Clemson Villa -Perfect for all Game Days!
Up to 6 guests
Airbnb$170
Vrbo$250
Average Nightly Rate
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5.0 (5)
Lakehouse 10 minutes from Clemson
Up to 6 guests
Airbnb$286
Vrbo$350
Average Nightly Rate
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5.0 (51)
Luxury on Lake Keowee - 2022 now available Memorial Day & FALL FOOTBALL
Up to 24 guests
Airbnb$700
Vrbo$700
Average Nightly Rate
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5.0 (95)
Lakefront Bible Study Get-a-way Winter-Spring Special
Up to 15 guests
Vrbo$393
Airbnb$418
Average Nightly Rate

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5.0 (32)
Frog Hollow Retreat @ Lake Hartwell
Up to 6 guests
Airbnb$164
Vrbo$189
Average Nightly Rate
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5.0 (14)
Friendship Cove Lake House with Private Dock, Kayaks, and More
Up to 14 guests
Airbnb$351
Vrbo$424
Average Nightly Rate

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5.0 (117)
Clemson Events Basecamp
Up to 6 guests
Vrbo$159
Airbnb$168
Average Nightly Rate
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5.0 (68)
Lake Keowee Lake Front Home ~ Wine and Art Gallery
Up to 9 guests
Airbnb$588
Vrbo$593
Average Nightly Rate
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5.0 (54)
Perfect Lake Hartwell Getaway - Gorgeous Lake Views!
Up to 16 guests
Airbnb$482
Vrbo$750
Average Nightly Rate
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5.0 (54)
Clemson Game Ready! 5 Miles To Death Valley On Lake Hartwell. NO CLEANING FEES!
Up to 8 guests
Vrbo$599
Airbnb$600
Average Nightly Rate
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5.0 (47)
Lake Keowee SC Vacation Home, up to 14 guests, private dock
Up to 14 guests
Vrbo$505
Airbnb$550
Average Nightly Rate
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5.0 (190)
😎Lake Front Private Retreat 15 min to Clemson🏈 Dock, Pdle boat, Kayaks, canoe
Up to 10 guests
Vrbo$278
Airbnb$320
Average Nightly Rate
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5.0 (90)
WHITE SAND BEACH, UV HVAC PROTECTED- NEW F. RING & PVT DOCK-DEEP WATER
Up to 12 guests
Vrbo$564
Airbnb$595
Average Nightly Rate
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5.0 (58)
Lakefront Keowee Retreat w/ Dock ~14 Mi to Clemson
Up to 10 guests
Vrbo$283
Airbnb$296
Average Nightly Rate
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5.0 (52)
Lake Hartwell Home w/ Dock < 10 Miles to Clemson!
Up to 8 guests
Airbnb$263
Vrbo$285
Average Nightly Rate
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5.0 (100)
Great Location! Close to town & amenities, just 10 miles from Clemson University
Up to 12 guests
Vrbo$504
Airbnb$550
Average Nightly Rate
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4.9 (40)
Lake Keowee Waterfront Home 15 miles from Clemson!
Up to 18 guests
Airbnb$496
Vrbo$514
Average Nightly Rate
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4.9 (117)
Private setting close to Clemson University
Up to 8 guests
Airbnb$149
Vrbo$150
Average Nightly Rate
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4.9 (40)
Lake Keowee Cabin 14 miles to Clemson
Up to 12 guests
Airbnb$607
Vrbo$643
Average Nightly Rate
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4.9 (11)
Lake Keowee waterfront cottage with flat walk to dock- convenient to Clemson
Up to 10 guests
Vrbo$450
Airbnb$525
Average Nightly Rate
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4.9 (80)
Best Lake Keowee Views and Private Boat Dock!
Up to 10 guests
Vrbo$385
Airbnb$425
Average Nightly Rate
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4.9 (67)
Lake Hartwell Home with Clemson Stadium Views
Up to 10 guests
Airbnb$325
Vrbo$325
Average Nightly Rate
  1. United States
  2. South Carolina
  3. Seneca Vacation Rental Price Comparison

Compare Airbnb vs. Booking.com vs. Vrbo prices for vacation rentals in Seneca, SC, USA

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