Best price vacation rentals in Defiance, MO, USA • 150 Listings
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Defiance, MO, USA Vacation Rentals | 

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5.0 (108)
Historical home in Downtown Washington
Up to 6 guests
Airbnb$289
Vrbo$295
Average Nightly Rate
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5.0 (25)
Augusta Studio at Halcyon Spa Bed & Breakfast
Up to 2 guests
Vrbo$101
Airbnb$123
Average Nightly Rate
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5.0 (7)
Cozy Wine Country Home [ Lodging only ... this is not an event venue ]
Up to 5 guests
Airbnb$216
Vrbo$216
Average Nightly Rate
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5.0 (4)
Cedar Haus - Downtown WashMo, Dog-Friendly, Wineries, Fenced Yard
Up to 18 guests
Vrbo$493
Airbnb$644
Average Nightly Rate
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5.0 (28)
Cozy 2 Bedroom 2 Bathroom Chalet Located in the Heart of Innsbrook
Up to 8 guests
Airbnb$374
Vrbo$379
Average Nightly Rate
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5.0 (63)
Hillside Cabin on 43 Acres w/ Private Lake & View!
Up to 4 guests
Airbnb$163
Vrbo$164
Average Nightly Rate
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5.0 (137)
Clean & Cozy Chalet in a Relaxing Wooded Scene. Stay & Find Your “Missing Peace”
Up to 5 guests
Vrbo$138
Airbnb$143
Average Nightly Rate

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5.0 (14)
Cardinal Shores Retreat Cottage by Sarah Bernard Chalets with Private Dock, F...
Up to 4 guests
Vrbo$243
Airbnb$249
Average Nightly Rate
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5.0 (20)
'Lucky Dawg' Pet-Friendly Abode Near St Louis!
Up to 6 guests
Vrbo$151
Airbnb$156
Average Nightly Rate

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5.0 (14)
Beautiful Cozy Amenity Haven-Heated Pool-Pool Table-Gym! Pets OK#3
Up to 4 guests
Airbnb$212
Vrbo$328
Average Nightly Rate
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5.0 (11)
Charming 1 bedroom 1 Bathroom Chalet located on the Fairway of Hole 3!
Up to 4 guests
Airbnb$301
Vrbo$305
Average Nightly Rate
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5.0 (5)
NEW! 'The Ruebling House' Bright + Modern Abode!
Up to 6 guests
Vrbo$122
Airbnb$150
Average Nightly Rate
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5.0 (9)
Flat, Lakefront chalet; Hottub Playground, Firepit, Wifi, and more 🖤
Up to 12 guests
Vrbo$400
Airbnb$405
Average Nightly Rate
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5.0 (10)
Longhorn Lakeside Chalet by Sarah Bernard Chalets, Private Dock, Kayaks and F...
Up to 8 guests
Vrbo$326
Airbnb$335
Average Nightly Rate
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5.0 (3)
NEW! ‘Bross Brother's Cabin’ w/ Wraparound Porch!
Up to 8 guests
Vrbo$316
Airbnb$328
Average Nightly Rate
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5.0 (4)
Boxcar2 apt.in Boutique Hotel minutes from highway
Up to 7 guests
Vrbo$195
Airbnb$197
Average Nightly Rate
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5.0 (3)
Boxcar1Eclectic pet friendly space sleeps 7
Up to 7 guests
Vrbo$207
Airbnb$207
Average Nightly Rate
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5.0 (4)
Turrach Ridge Escape, Innsbrook, A Woodland Waterfront Chalet Retreat
Up to 10 guests
Airbnb$264
Vrbo$264
Average Nightly Rate
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5.0 (4)
Boxcar4 rm Sleep7! Pet/family friendly by 6Flags
Up to 7 guests
Vrbo$210
Airbnb$210
Average Nightly Rate
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5.0 (13)
The Music Box Chalet - Innsbrook Resort
Up to 6 guests
Airbnb$250
Vrbo$254
Average Nightly Rate
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5.0 (4)
Yacht2 2nd flr apt.in Boutique Hotel near adventure
Up to 12 guests
Vrbo$300
Airbnb$303
Average Nightly Rate
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5.0 (1)
Yacht1 Apt. in Eclectic hotel. Pet/family friendly
Up to 12 guests
Airbnb$265
Vrbo$271
Average Nightly Rate
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5.0 (69)
LESS THAN 8 MILES TO PURINA EVENT CENTER, PET FRIENDLY WITH FENCED AREAS
Up to 8 guests
Vrbo$254
Airbnb$257
Average Nightly Rate
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5.0 (21)
Spacious and Comfortable Home in Saint Peters
Up to 8 guests
Airbnb$243
Vrbo$260
Average Nightly Rate
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5.0 (31)
Stunning Lakeside Retreat at Innsbrook w/ Swing, Canoe and 3 Kayaks
Up to 12 guests
Airbnb$400
Vrbo$400
Average Nightly Rate
  1. United States
  2. Missouri
  3. Defiance Vacation Rental Price Comparison

Compare Airbnb vs. Booking.com vs. Vrbo prices for vacation rentals in Defiance, MO, USA

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